rats and mice host:extoxnet.orst.edu

Listing 1 - 10 from 56 for rats and mice

EXTOXNET PIP - AMITROLE
... of pregnant rabbits, rats, and mice exposed to amitrole, but only at doses high enough to also produce signs of toxicity in the mothers [14]. Atrophy of the thymus and spleen occurred at high ... and liver tumors in rats and mice after lifetime high dose exposures [3,14,18]. Organ toxicity: Animal studies have shown that amitrole's main effects are on the thyroid and liver. Fate in humans and ...
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EXTOXNET PIP - CLOMAZONE
... rats and 2077 mg/kg in male rats [8,58]. The oral LD50 for Command 4EC is slightly higher: 1406 mg/kg in female rats and 2343 in male rats ... rats [58]. The inhalation LC50 for Command 4EC in rats is 4.5 to 4.7 mg/L [58]. Chronic toxicity: In 2-year feeding studies with rats and mice, and ...
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EXTOXNET PIP - CYANAZINE
... rats and mice at doses up to 225 mg/kg/day showed that cyanazine decreases body weight gain and increases liver weights [11]. Reproductive effects: Cyanazine caused decreases in maternal body weight gain in rats ...
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EXTOXNET PIP - DEMETON-S-METHYL
... tumor causing compounds and most organophosphate compounds tested do not cause tumors in rats and mice (1). Organ Toxicity: Chronic exposure to demeton-s-methyl can cause inner ear irritation and excess blood in the tissue of respiratory organs. Rats receiving 15 daily ...
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EXTOXNET PIP - DICHLORVOS
... may be due to rapid metabolism and excretion [2]. Carcinogenic effects: Dichlorvos has been classified as a possible human carcinogen because it caused tumors in rats and mice in some studies but not others [11]. When dichlorvos was administered by gavage (stomach tube) to mice for 5 days per week for 103 ...
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EXTOXNET PIP - DIFLUBENZURON
... rats and mice is greater than 4640 mg/kg, and the dermal LD50 is greater than 10,000 mg/kg in rats and greater than 4000 mg/kg in rabbits. It is nonirritating to skin and slightly irritating to eyes [8]. Chronic toxicity: Rats ... be teratogenic. Newborn rats and rabbits did ...
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EXTOXNET PIP - DINOSEB
... reported to adversely affect reproduction in rats and mice at levels that are commonly found among occupational workers. Decreased sperm count and abnormal sperm shape were observed in male rats and mice after 3 weeks at low exposure levels (about 10 mg/kg/day) for 30 days [84]. In a separate study, rats ...
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EXTOXNET PIP - DISULFOTON
... rats and 15.9 mg/kg in male rats [60]. The inhalation LC50 for 1 hour is 0.3 mg/L in male rats [13]. Chronic toxicity: Rats ... rats and mice fed high doses for 2 years did not show significant tumor growth [59,60]. Organ toxicity: Continual daily absorption may cause flu-like symptoms, loss of appetite, weakness, and ...
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EXTOXNET PIP - ETHYLENE DIBROMIDE (EDB)
... of EDB to rats and chicks caused changes in the livers of these animals within 22 hours [176]. In rats, inhalation of small concentrations of EDB vapors depresses weight gain, and slightly higher ... rats and mice who were exposed to various levels of EDB vapors for 23 hours a day during the sensitive period of gestation [178]. At all doses, both rats and mice showed body weight decreases, and ...
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EXTOXNET PIP - ETHION
... rats of 208 mg/kg, and for technical ethion of 21 to 191 mg/kg [8,13]. Other reported oral LD50 values (for the technical product) are 40 mg/kg in mice and ... and unscheduled DNA synthesis indicate that ethion is not mutagenic [62,63]. Carcinogenic effects: Ethion was not carcinogenic in rats and mice [7]. There was no increase in the incidence of tumors in rats ...
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